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KMID : 0870420020060020117
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Korean Journal of Hepato-Biliary-Pancreatic Surgery
2002 Volume.6 No. 2 p.117 ~ p.122
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Concomitant Splenectomy during Hepatectomy in Patients with Liver Cirrhosis and Thrombocytopenia
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Shin Myung-Ha
Lim Yang-Soo
Hwang Yoon-Jin
Kim Yang-Il
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Abstract
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Background/Aims: Resection of hepatocellular carcinoma in patients with liver cirrhosis and thrombocytopenia is risky. The benefit of concomitant splenectomy in cirrhotic patients is controversial.
Methods: To evaluate the efficacy of concomitant splenectomy in patients with liver cirrhosis and thrombocytopenia, 13 cirrhotic patients with thrombocytopenia (platelet count< or =80,000/mm3) were divided by two groups (Group I: the patients without concomitant splenectomy during hepatectomy, Group II: the patients with concomitant splenectomy). Intraoperative and postoperative parameters were retrospectively reviewed.
Results: Group II patients needed less amount of postoperative blood transfusion (Group I: 178.3+/-150 ml PRC in 3 patients, Group II: 107.1+/-100 ml in 2 patients, p=0.012, p= 0.041) and the platelet count was elevated to above 250,000/mm3 (p=0.003) and showed lower serum bilirubin level (p=0.037) within 1 week of operation in group II patients.
Conclusion: The concomitant splenectomy during in patients of liver cirrhosis with thrombocytopenia may improve liver function and elevate platelet count.
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KEYWORD
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Concomitant splenectomy, Liver cirrhosis, Thrombocytopenia
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